Aerobic Degradation of Dinitrotoluenes and Pathway for Bacterial Degradation of 2,6- Dinitrotoluene.

Abstract

An oxidative pathway for the mineralization of 2,4-dinitrotoluene (2,4-DNT) by Burkhoderia sp. strain DNT has been reported previously. We report here the isolation of additional strains with the ability to mineralize dinitrotoluene (2,6-DNT) by a different pathway. Burkizodena cepacia strain JS85O and Hydrogenephaga palleronii strain JS863 grew on 2,6-DNT as the sole source of carbon and nitrogen. The initial steps in the pathway metabolites through mass spectroscopy and nuclear magnetic resonance. 2,6- DNT was converted to 3-methyl-4-nitrocatechol by a dioxygenation reaction accompanied by the release of nitrite. 3-Methyl-4- nitrocatechol was the substrate for extradiol ring cleavage yielding 2-hydroxy-5-nitro-6-oxohepta-2,4-dienoic acid, which was converted to 2-hydroxy-5 -nitropenta-2,4-dienoic acid.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jan 01, 2000
Accession Number
ADA379526

Entities

People

  • George C. Paoli
  • Jim C. Spain
  • Shirley F. Nishino

Organizations

  • Air Force Research Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Bacteria
  • Chemical Synthesis
  • Chemistry
  • Liquid Chromatography
  • Magnetic Resonance
  • Mass Spectra
  • Mass Spectrometry
  • Mass Spectroscopy
  • Metabolism
  • Metabolites
  • Nuclear Magnetic Resonance
  • Organic Chemistry
  • Resonance
  • Spectra
  • Spectroscopy

Fields of Study

  • Environmental science

Readers

  • Agricultural Chemistry/Soil Science
  • Analytical Chemistry
  • Microbial Pathology