Diffusable Phase-Setting Signals of the Biological Clock

Abstract

The encapsulation membranes fabricated from solutions containing Poly(acrylonitrilevinylchloride) (PAN-PVC) (85%) and polyethylene oxide (PEO) (15%) were tested for restoration of circadian activity rhythms to animals whose own SCN has been ablated. This work shows that the transplanted SCN, like neural pacemakers of Drosophilia and silk moths, can sustain circadian activity rhythms by means of a diffusible signal.

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Document Details

Document Type
Technical Report
Publication Date
Mar 31, 1999
Accession Number
ADA380296

Entities

People

  • Patrick Tresco
  • Rae Silver

Organizations

  • Barnard College

Tags

Communities of Interest

  • Advanced Electronics

DTIC Thesaurus Topics

  • Animals
  • Biological Rhythms
  • Brain
  • Cell Encapsulation
  • Cells
  • Chronobiology
  • Circadian Rhythms
  • Electron Microscopy
  • Encapsulation
  • Lepidoptera
  • Medical Personnel
  • Neurosciences
  • New York
  • Pacemakers
  • Peptides
  • Transplants

Readers

  • Circadian Sleep-Wake Regulation and Chronobiology
  • Nanocomposite Materials Science
  • Neuroscience

Technology Areas

  • Biotechnology