Assessment of the Genotoxic Potential of Dredged Material

Abstract

This technical note describes an approach for assessing the genotoxic potential of dredged material. The use of integrated batteries of rapid and mechanistically interpretable in vitro and in vivo assays in a tiered approach is fundamental to applied toxicology. The research described here brings this approach to the testing of sediments. Work completed to date and future work will mesh to form an advanced and cost effective methodology. The purpose of this methodology is to increase the accuracy of environmental risk assessments and facilitate making decisions concerning open-water disposal of dredged material.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1996
Accession Number
ADA381031

Entities

People

  • Michael E. Honeycutt
  • Robert M. Engler
  • Victor A. Mcfarland

Tags

DTIC Thesaurus Topics

  • Aromatic Hydrocarbons
  • Cancer
  • Cell Line
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Cultured Cells
  • Dna Repair Enzymes
  • Ecotoxicology
  • Environmental Pollutants
  • Environmental Protection
  • Materials
  • Neoplasms
  • Polychlorinated Biphenyls
  • Risk Analysis
  • Test Methods
  • Waterways

Readers

  • Coastal and Marine Engineering/Sediment Transport/Hydraulic Engineering
  • Computational Modeling and Simulation
  • Toxicology/Environmental Toxicology