Risk Factors for Osteoporosis and Oral Bone Loss in Postmenopausal Women

Abstract

The overall purpose of this study is to determine the relationship between skeletal and oral bone density, identify factors influencing bone loss, and determine the relationship between osteoporosis and oral bone loss, periodontal disease and tooth loss. We hypothesize that reduction in bone density leading to osteoporosis, plays a significant role in increasing susceptibility to destructive periodontitis and tooth loss. Sensitive and accurate measures of skeletal and oral bone mineral density, periodontal disease and tooth loss will be used. A wide variety of other risk factors for both osteopenia and periodontal disease will be assessed. A total of 1300 subjects are being recruited from an ongoing NIH funded study cohort, the Women's Health Initiative (WHr). Preliminary research findings from our pilot study determined that bone loss in the hip or spine is strongly associated bone loss in the jaw. Also, that bone loss in the hip was associated with tooth loss even when controlling for factors such as age, menopause, estrogen use, body mass and smoking We have just completed year three of a four year study. Data collection will continue into year-4, as such, findings are not yet available to report.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1999
Accession Number
ADA381140

Entities

People

  • Jean Wactawski-Wende

Organizations

  • State University of New York

Tags

DTIC Thesaurus Topics

  • Bone Diseases
  • Bone Fractures
  • Diseases And Disorders
  • Health
  • Health Care
  • Health Services
  • Medical Personnel
  • Mouth Diseases
  • Musculoskeletal Physiology
  • Osteoporosis
  • Risk Factors
  • Teeth
  • Tooth Diseases

Fields of Study

  • Medicine

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