Lifetime Alcohol Exposure and Breast Cancer
Abstract
This case-control study examines breast cancer risk in relation to lifetime alcohol consumption. Subjects are 960 pre-and post-menopausal women, age 35-79, from Erie and Niagara counties in New York State, with incident, pathologically confirmed breast cancer. Most controls have been interviewed as part of another study that has just ended. Controls are randomly selected and frequency matched to cases on age, race and county of residence. Subjects receive a computerized interview, which focuses on in-depth lifetime alcohol consumption history. Potential confounding factors are also assessed. A specimen bank is used to store biological samples for future research of serum and urinary markers of hormones, hormone metabolites, vitamins, genetic polymorphisms and blood levels of antioxidants and oxidative stress. This study provides an important opportunity for an efficient examination of alcohol and other risk factors, particularly genetic variability, in relation to breast cancer risk, with potential for clarification of a significant public health problem. Since the inception of the study, 620 breast cancer cases and 2,007 controls have been interviewed and blood samples stored for 520 cases and 1,862 controls. Data collection is still underway, therefore there are no conclusions to report at this time.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 1999
- Accession Number
- ADA381282
Entities
People
- Jo L Freudenheim
Organizations
- State University of New York