IGF-1, 1,25 (OH)2 Vitamin D, and Prostate Cancer

Abstract

High circulating levels of insulin-like growth factor 1 (IGF-1) or low levels of 1,25(OH)2 vitamin D (1,25(OH)2D) are associated with an increased risk of prostate cancer. This project examines whether specific dietary patterns are related to prostate cancer by influencing levels of IGF-1 and 1 ,25(OH)2D; specifically whether high energy and protein intakes increase IGF-1 and high intakes of calcium, phosphorus, and animal protein decrease 1 ,25(OH)2D levels. The relationships between dietary factors and circulating IGF-1 and 1,25(OH)2D are being examined using the Massachusetts Male Aging Study, for which dietary data and blood samples have already been collected.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1999
Accession Number
ADA383489

Entities

People

  • Edward L. Giovannucci

Organizations

  • Harvard T.H. Chan School of Public Health

Tags

DTIC Thesaurus Topics

  • Animals
  • Biomedical Research
  • Chemical Compounds
  • Data Analysis
  • Energy
  • Growth Factors
  • Health
  • Laboratory Animals
  • Massachusetts
  • Materials
  • Neoplasms
  • Prostate
  • Prostate Cancer
  • Public Health
  • Recombinant Dna
  • Statistical Analysis
  • Vitamin D

Fields of Study

  • Medicine

Readers

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