Ventilation-Perfusion Alterations after Inhalation Injury in an Ovine Model

Abstract

Ventilation- perfusion alterations after smoke inhalation injury in an ovine model. J. Appl. PhysioL. 81(5): A 2250-2259, 1996. To study the pathophysiological mechanism of progressive hypoxemia after smoke inhalation injury, alterations in ventilation-perfusion ratio (VA/Q) were studied in an ovine model by using the multiple inert gas elimination technique. Because ethane was detected in expired gas of some sheep, we replaced ethane with krypton, which was a unique application of the multiple inert gas elimination technique when one of the experimental gases is present in the inspirate. Severity-related changes were studied 24 h after injury in control and mild, moderate, and severe inhalation injury groups.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1996
Accession Number
ADA383517

Entities

People

  • Arthur D. Mason Jr.
  • Hisashi Ikeuchi
  • Peter D. Wagner
  • Takeshi Shimazu
  • Tetsuo Yukioka

Organizations

  • United States Army Institute of Surgical Research

Tags

DTIC Thesaurus Topics

  • Airway Management
  • Analysis Of Variance
  • Anesthesia
  • Burns
  • Data Science
  • Detectors
  • Dielectric Gases
  • Information Science
  • Lung Diseases
  • Mass Spectrometry
  • Multivariate Analysis
  • Partial Pressure
  • Physiology
  • Regression Analysis
  • Respiratory Physiological Phenomena
  • Spectrometry
  • Wounds And Injuries

Readers

  • Cardiovascular Physiology
  • Immunology and Pathology
  • Organic Chemistry