Breast Tumor Detection Utilizing Novel in situ Amplification Systems

Abstract

Although existing radiographic, ultrasound and MRI modalities for the detection of breast canter are useful, they are less than ideal. Nuclear medicine approaches using radiolabled anti-breast tumor antibodies and other radiolabeled agents have met with similar mixed results. Accordingly there is a need for improved approaches for the detection and treatment of breast tumors. This work explored several novel approaches using DNA for specific targeting and signal amplification. The work completed during this period will serve as the-foundation for future work in this area.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1999
Accession Number
ADA383601

Entities

People

  • Cassandra L. Smith

Organizations

  • Boston University

Tags

DTIC Thesaurus Topics

  • Amplification
  • Antibodies
  • Breast Cancer
  • Cells
  • Chemistry
  • Detection
  • Dna Sequence Analysis
  • Genetic Structures
  • Materials
  • Molecules
  • Neoplasms
  • Nucleic Acids
  • Recombinant Dna
  • Sequence Analysis
  • Small Molecules
  • Targeting
  • Therapy

Fields of Study

  • Medicine
  • Physics

Readers

  • Molecular Genetics
  • Oncology (Cancer Research).
  • Oncology and Biomarker-Based Cancer Detection.