Services to Operate a Hemoglobin Production Facility and a Red Blood Cell Storage Laboratory
Abstract
The Bionetics Corporation operated and maintained a laboratory, which performed red blood cell preservation research for the Blood Research Detachment, Walter Reed Army Institute of Research at Building 503, Walter Reed Forest Glen Annex, Silver Spring, MD 20910. Contract staff completed one clinical trial and four in vitro protocols. The clinical trial was an evaluation of an investigational system for processing frozen red blood cells, which would extend the post-thaw shelf life from 1 to 15 days. The red cells processed by the system exceeded the required minimum of >75% survival 24 hours after autologous transfusion and < 1% hemolysis in the final product. The four in vitro protocols were designed to optimize the experimental additive solution storage system, expand our understanding of the mechanisms of action and test its utility for post-thaw storage of previously frozen red cells. Three manuscripts describing the results of research completed previously were published and a fourth is in press. The Bionetics Corporation advanced the mission of the Blood Research Detachment and the Walter Reed Army Institute of Research.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2000
- Accession Number
- ADA384261
Entities
People
- Lloyd Lippert