Long Term Whole-Body Retention After High Level CESIUM-137 Administration to Rats

Abstract

A long-term component of Cs-137 whole-body retention in rats has been found. The early retention kinetics, through approximately 120 days following intraperitoneal injection, show similarities to previously reported data from other investigators. However, use of higher levels of injected isotope has enabled measurement of body burdens for periods approaching one year and has resulted indiscovery of a component of loss which has a half-life of 102 days. This retention component represents only 1. 5 x 10(-4)of the initial body burden and would not contribute significantly to the radiation dosage. It does, however, represent a fraction of whole-body retention which has not been reported for rodents and which may be present in other species. Certain broad physiological parameters such as age, body weight, and sex are discussed relative to the observed retention kinetics.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1967
Accession Number
ADA385494

Entities

People

  • Randi L. Thomas
  • Robert G. Thomas

Organizations

  • Lovelace Foundation

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Animals
  • Body Weight
  • Contractors
  • Digestive System Processes
  • Elimination
  • Fission Products
  • Kinetics
  • Laboratory Animals
  • Measurement
  • Metabolism
  • New Mexico
  • Radiation
  • Radiation Effects
  • Radiation Sickness
  • Radioactive Materials
  • Radioactivity
  • United States

Readers

  • Cardiovascular Physiology
  • Combustion science or combustion engineering.
  • Military Mobilization and Reserve Forces Studies.