MR Measurement of Breast Tissue's Anisotropic Mechanical Properties

Abstract

The purpose of this grant was to develop methods to estimate the mechanical properties of tissue, especially the elasticity, in vivo. These methods will be used to evaluate mechanical properties, such as the elasticity, as indicators of breast cancer. MR images were used to measure the displacement of tissue resulting from a low frequency vibration of the tissue. We developed methods of vibrating tissue in the magnetic field of the MR system, developed the MR pulse sequences that measure the resulting displacement and developed the an algorithm to reconstruct the elasticity from the measured displacements. The algorithm to reconstruct the elasticity allows spatial resolution a factor of at least ten better than previous methods.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1999
Accession Number
ADA385692

Entities

People

  • John B. Weaver

Organizations

  • Dartmouth College

Tags

Communities of Interest

  • Biomedical
  • Ground and Sea Platforms

DTIC Thesaurus Topics

  • Algorithms
  • Differential Equations
  • Elastic Properties
  • Finite Element Analysis
  • Frequency
  • Health Services
  • Image Processing
  • Imaging Techniques
  • Mechanical Properties
  • Mechanics
  • Medical Personnel
  • Modulus Of Elasticity
  • Partial Differential Equations
  • Physical Properties
  • Three Dimensional
  • Two Dimensional
  • Wave Propagation

Fields of Study

  • Physics

Readers

  • Medical Imaging.
  • Structural Dynamics.