Identification of Cellular and Molecular Markers of Prostate Cancer Progression in Racial-Ethnic Minorities
Abstract
This is a study looking at the differences in tumor behavior (molecular and cellular behavior) observed in prostate cancer arising in men of different racial groups. Characterization of those pathways involved in tumor invasion, metastasis, and loss of growth control, including their regulation and interconnections, should provide insight into the behavior of prostate cancer. We have defined a cohort of men with prostate cancer, 400 African-Americans and 300 Latino men. These men had already signed a tissue release form, which we believed would suffice for this study to allow us to secure tissue release from hospitals. However, due to the nature of this particular study and new language requirements in the consents as required by our Institutional Review Board, new consents had to be developed, substantially delaying start up for this study. 210 men have signed the forms and returned them to us by mail. We have given 163 tissue release request forms to the Tissue Procurement Core Resource. We are in the process of calling subjects and tracking cases through our cancer registry follow-up department. The first tissues are now being received and we have begun the immunohistochemical as says on these samples.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 01, 1999
- Accession Number
- ADA385809
Entities
People
- Richard J. Cote
Organizations
- University of Southern California