Secretion of Heterologous Proteins from Escherichia coli

Abstract

The primary objective of the research performed under this grant was to gain a fuller understanding of the requirements for export of heterologous proteins from Escherichia coli. The long term goal would be to engineer bacteria to secrete cloned proteins to the periplasmic space either to improve the overproduction and purification of such proteins or to facilitate bioremediation efforts using bacteria that can export degradative enzymes.

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Document Details

Document Type
Technical Report
Publication Date
Dec 14, 2000
Accession Number
ADA385862

Entities

People

  • Ann M. Flowers

Organizations

  • University of North Dakota

Tags

DTIC Thesaurus Topics

  • Amino Acids
  • Bacteria
  • Bacteriophages
  • Biological Sciences
  • Bioremediation
  • Engineers
  • Escherichia
  • Escherichia Coli
  • Grand Forks
  • Health
  • Health Care
  • Military Research
  • North Dakota
  • Scientists
  • Secretion
  • Sequences
  • Suppressors

Fields of Study

  • Biology
  • Engineering

Readers

  • Microbial Pathology
  • Molecular Genetics

Technology Areas

  • Biotechnology
  • Biotechnology - Bioremediation
  • Space