Breast Images with Diffusing Light Waves
Abstract
Our work over the last year aimed to develop and assess the utility of various theoretical and experimental diffuse light imaging schemes for tumor detection and characterization within the human breast. We have theoretically and numerically investigated the angular spectrum approach in the parallel plate (compressed breast) geometry. One paper investigated the use of depth dependent regularization and mathematical filtering methods to improve the fidelity of these projection images in the presence of noise. In a related publication we documented a group of refinements to the diffraction tomographic techniques. On the experimental side we have built a soft compression plate apparatus for diffuse optical tomography of the breast. The device was used to experimentally to test the angular spectrum and other theoretical approaches. Through this work we uncovered some technical limitations of diffuse optical tomography based on the angular spectrum approach, and, importantly, we developed other schemes for improved breast imaging. In this vein we derived a new integro-differential equation for bounded media within the diffusion approximation, which makes possible full 3D reconstruction in the compressed breast geometry.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 01, 1999
- Accession Number
- ADA385922
Entities
People
- Arjun Yodh
Organizations
- University of Pennsylvania