Cancers Missed on Mammography

Abstract

Observer error in reading screening mammograms has been identified as a significant factor in delayed diagnosis of breast cancer. The magnitude of the problem is estimated to be about 30% of potentially detectable cancers are overlooked for one or more years before detection. Computer-aided diagnosis (CAD) programs have been developed to aid radiologists in the detection task, and pre-clinical studies have shown that CAD applied to digitized mammography films can flag about 50% of radiologists' observational oversights. Preliminary study has also shown a wide variability in radiologist observer performance. The purpose of this investigation is to test how many additional cancers are detected by radiologists using CAD, in an observer study using an enriched mixture of cancers. A pilot study has been completed and the results were used to plan the full observer study: 400 cases containing 75 cancers with 6 radiologists. Final case selection is being done and observers are being recruited.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2000
Accession Number
ADA386180

Entities

People

  • Robert Nishikawa

Organizations

  • University of Chicago

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biomedical Research
  • Breast Cancer
  • Cancer Screening
  • Computer-Aided Diagnosis
  • Computers
  • Data Analysis
  • Databases
  • Detection
  • Electronic Mail
  • Health Care
  • Mammography
  • Medical Personnel
  • Neoplasms
  • Observers
  • Physicians
  • Pilot Studies
  • Universities

Fields of Study

  • Medicine
  • Physics

Readers

  • Oncology and Biomarker-Based Cancer Detection.