The Effects of Morphine Sulfate on Agglutination, Clot Formation and Hemolysis in Packed Red Blood Cells
Abstract
Morphine sulfate is an opium alkaloid narcotic frequently used on patients suffering from acute and chronic disease processes. Often patients receiving either acute or long- term pain therapy with morphine require concomitant blood transfusion therapy. Based on current American Association of Blood Banks guidelines the addition of any medication other than normal saline to packed red blood cells is strictly prohibited. This restriction can lead to unwanted delays in medication schemes when patients with limited intravenous access are in need of both therapies at the same time. Few studies exist that have investigated the effects of morphine sulfate on packed red blood cells. Most of these have, in a limited manner, presented contrasting evidence on the efficacy of this practice.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 18, 2001
- Accession Number
- ADA387389
Entities
People
- Brian K. Estavillo
Organizations
- Uniformed Services University of the Health Sciences