A Controlled Study Using Acupuncture as an Adjuvant to Treat Chemotherpay-Induced Nausea and Vomiting

Abstract

This is a randomized, double blind controlled study designed to assess the effects of Electroacupuncture (EA) on nausea and vomiting induced by chemotherapy in breast cancer patients. The primary aim of this study is to evaluate the usefulness of HA as an adjuvant on N/v in chemotherapy patients who do not respond to conventional antiemetics. Seventy five outpatients will be recruited from the University of Maryland Baltimore (UMB) Cancer Center who have shown refractory to 5-HT3 antiemetic and randomized into three treatment groups (n--25 per group) : (1) HA: 10 Hz, 10 min, (2) HA: 100 Hz, 10 min, and (3) a sham acupuncture control group. Research team personnel have been hired and recruitment began in January 2000. As of August 31, forty-two patients have been screened, six were eligible, and four have consented to go on protocol and have now completed the study. The study has experienced difficulty with obtaining sufficient recruitment due to a relatively small breast cancer patient pool at the UMS Cancer Center. An amendment IRE requesting permission to expand the eligibility criteria to include all cancer chemotherapy patients has recently approved by IRE and DOD, and the expanded recruitment procedure will begin in Oct. 2000.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2000
Accession Number
ADA387609

Entities

People

  • Lixing Lao

Organizations

  • University of Maryland, Baltimore

Tags

DTIC Thesaurus Topics

  • Analgesia
  • Antiemetics
  • Biomedical Research
  • Breast Cancer
  • Chemotherapy
  • Clinical Trials
  • Department Of Defense
  • Electronic Mail
  • Information Operations
  • Institutional Review Board
  • Instructors
  • Maryland
  • Medical Personnel
  • Neoplasms
  • Quality Of Life
  • Universities

Fields of Study

  • Medicine

Readers

  • Brain and Cognitive Science; Experimental Psychology; Cognitive Neuroscience
  • Clinical Trial Research.
  • Oncology