A Randomized Prospective Trial Comparing Paravertebral Block and General Anesthesia for Operative Treatment of Breast Cancer
Abstract
The goals of the study are to evaluate the role of paravertebral block regional anesthesia in patients undergoing operative treatment of breast cancer. Experience to date has shown that this anesthetic modality is safe and effective, and associated with excellent postoperative pain control and minimization of nausea and vomiting associated with general anesthesia. Using a prospective randomized trial carried out at three institutions, we propose to measure quality of life variables including pain, postoperative nausea and vomiting, mood, and functional status in patients undergoing breast surgery with the traditional techniques of general anesthesia versus the regional technique of paravertebral block. The preliminary phase of this trial, which establishes safety and efficacy in performing the block technique, is ongoing. Once adequate experience in performing the paravertebral block is obtained, we will initiate the study portion of the trial by randomizing patients undergoing surgery to either general anesthesia or paravertebral block. Outcomes will be assessed using validated study instruments, which are included with the report.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 01, 2000
- Accession Number
- ADA387671
Entities
People
- Christina R. Weltz
Organizations
- Icahn School of Medicine at Mount Sinai