Computer-Aided Diagnosis and Feature-Guided Data Reduction Systems in Mammography

Abstract

We have been conducting the pilot clinical study to evaluate the effects of CAD on radiologists' reading of screening mammograms this year. We have analyzed the results of about 1,300 cases. The CADView system detected 100% (18/18) of the lesions that were recommended for biopsy in both sites, all fine needle biopsy cases (5/5) at the GU site, and missed only one of the fine needle biopsy cases (4/5) at the UM site. The CAD system detected both malignant cases at the UM site, whereas causing 19 additional callbacks and 1 additional benign biopsy. The CAD system detected all three cancers at the GU site, including one additional cancer that was not originally called by the radiologist, and only caused 2 additional callbacks. The CAD system also detected 74% (34/46) of the short-term follow up cases at the two sites. Since the number of cases collected so far is still small, we have not performed statistical analysis on the data yet. We will continue to collect cases at the UM and GU sites in the coming year. Two observer performance studies have been conducted for the CAD-guided image compression project. It was found that the proposed method with adequate bit rate will fully preserve the quality of microcalcifications and suspected microcalcifications without sacrificing the edge sharpness and overall image quality at an area-equalized bit-rate of about 0.4 bit/pixel. The CAD-guided compression can therefore reduce the image transmission and storage requirements for digital mammograms by a factor of about 30 without causing observable degradation of image quality. It can be an effective image compression method for picture archiving and communication and facilitate the implementation of telemammography and digital mammography.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2000
Accession Number
ADA388204

Entities

People

  • Heang-Ping Chan

Organizations

  • University of Michigan

Tags

Communities of Interest

  • Energy and Power Technologies
  • Engineered Resilient Systems

DTIC Thesaurus Topics

  • Artificial Intelligence
  • Computational Science
  • Computer Programming
  • Computer Programs
  • Computer Vision
  • Computers
  • Data Compression
  • Data Processing
  • Data Science
  • Databases
  • Image Processing
  • Information Processing
  • Information Science
  • Medical Personnel
  • Pattern Recognition
  • Self Organizing Systems
  • Statistical Analysis

Fields of Study

  • Medicine
  • Physics

Readers

  • Oncology and Biomarker-Based Cancer Detection.