Energy- and Intensity-Modulated Electron Beam for Breast Cancer Treatment
Abstract
This project is aimed at exploring energy- and intensity-modulated radiotherapy (EIMRT) to deliver dose distributions that closely match the target volume and minimize the dose to critical normal structures. The scope includes (I) to characterize electron beams from Helium-filled accelerators for EIMRT, (2) to develop optimization algorithms for EIMRT using these electron beams, (3) to verify these optimized dose distributions using the Monte Carlo simulation technique, and (4) to compare the optimized dose plans obtained by EIMRT with conventional treatment plans and those obtained by photon intensity- modulated radiotherapy (IMRT). During the first year research, we have performed accurate Monte Carlo simulations of the electron beams in He-filled accelerators. Our results demonstrated that electron beams could be modulated to deliver superior dose distributions for EIMRT. We have implemented practical source models for clinical application and beam commissioning. Different dose algorithms have been compared for "Inverse treatment planning" beamlet calculations. The results confirmed that the Monte Carlo method is needed to generate the dose distributions for EIMRT. Further studies will be performed to verify the dose plans for realistic patients. The outcome will determine whether EIMRT offers a significant advantage over conventional photon/electron treatment and over photon IMRT.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 1999
- Accession Number
- ADA388427
Entities
People
- Ma M. Chang
Organizations
- Stanford University