Quantitative Three-Dimensional Ultrasonic Mammography
Abstract
The goal of this research, improved diagnosis of breast cancer by quantitative, high-resolution two- and three-dimensional ultrasonic imaging, is being reached by a thorough program that synthesizes recent advances in tissue modeling, adaptive imaging, instrumentation, and signal processing. The goal of three-dimensional quantitative imaging is currently being achieved using novel time-domain inverse scattering methods invented by the Principal Investigator and coworkers. Nonlinear forms of these methods provide a robust and efficient approach to adaptive imaging, based on compensation for three-dimensional scattering from actual breast tissue structure. A crucial aspect of the research is the use of realistic tissue models for ultrasonic propagation through breast tissue. Tissue modeling techniques employ tissue maps obtained from specimen cross sections as well as from newly available high-resolution volume photographic data. Calculated scattering from these tissue models provides accurate characterization of ultrasonic propagation within breast tissue and realistic data for testing of quantitative imaging algorithms. Synthesis of these breakthroughs will make possible new mammographic applications of ultrasound that will provide clinicians with previously unavailable quantitative information and image detail.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 2000
- Accession Number
- ADA389542
Entities
People
- T. D. Mast
Organizations
- Pennsylvania State University