Physiological Stress Reactivity and Breast Cancer
Abstract
The objective of the present program of research is to study physiological processes that may mediate the links between psychological states and cancer. Specifically, the present study is designed to conduct an investigation of the cross-sectional associations between indices of stress reactivity and psychological coping styles in women with breast cancer and matched healthy controls. The aims of the project are: (1) To quantify parameters of biological reactivity to a behavioral stress paradigm in women with and without breast cancer; (2) To examine (a) group differences between women with and without breast cancer in biological stress reactivity, and (b) the effects of menopause and familial risk on biological stress reactivity and emotional expression; and (3) To develop the methodology and obtain preliminary data which could justify subsequent, prospective research with high-risk populations. For the period covered in this report, all pilot testing has been complete, the recruitment and assessment of research subjects in the study protocol is underway, a relational database has been completed, and biosamples have been stored at -70 degrees C for assays.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2000
- Accession Number
- ADA389900
Entities
People
- Pathik D. Wadhwa
Organizations
- University of Kentucky