Impact of BRCA1/2 Testing on Marital Relationships

Abstract

The present study is a prospective examination of the impact of genetic testing for breast-ovarian cancer susceptibility on marital relationships and the quality of life of husbands. Participants are women (age 18 and older) who are members of families in which a disease conferring mutation has been identified and their spouses. Interviews of husbands and wives are completely by telephone prior to receiving test results as well as 1-, 6-, and 12-months after test disclosure. The preliminary data showed that wives (n=49) were more likely to use avoidance have intrusive thoughts and experience psychological distress compared to husbands (n=35). Wives also rated higher marital satisfaction. The husbands scored lower at baseline on four of the measures of interest (the presence of intrusive thoughts, general psychological distress, state anxiety, and marital adjustment) than 1-month after follow-up (n=6). The results of the preliminary analysis suggest that husbands may experience less psychological distress than wives at the baseline assessment (pre-mutation disclosure). However, the level of distress may increase for the husbands within one month of learning of the wife's mutation status. Further analysis when more disclosures have been completed will elucidate the association between mutation status outcome and these psychological measures.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 2000
Accession Number
ADA389905

Entities

People

  • Sharon Manne

Organizations

  • Fox Chase Cancer Center

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Breast Cancer
  • Data Analysis
  • Department Of Defense
  • Diseases And Disorders
  • Education
  • Genetic Phenomena
  • Genetic Testing
  • Genetics
  • Health Services
  • Institutional Review Board
  • Medical Genetics
  • Medical Personnel
  • Psychology
  • Social Psychology
  • Statistical Analysis
  • Surveys

Fields of Study

  • Psychology

Readers

  • Brain and Cognitive Science; Experimental Psychology; Cognitive Neuroscience
  • Molecular and genetic basis of cancer.
  • Rehabilitation and Prosthetic Care for Military Service Members and Veterans with Limb Loss or Disability.

Technology Areas

  • Biotechnology