Ovarian Cancer Prevention Program
Abstract
The goals of this research are to develop interdisciplinary studies of the etiology, biology and prevention of ovarian cancer. Project I, Ovarian Cancer Consortium has registered 293 participants including 97 ovarian cancer patients representing 165 families. The Core Laboratory has collected, processed and banked biospecimens from 235 subjects. Project II, Facilitating Decision Marking About Prophylactic Oophorectomy: baseline data on 68 women are available for preliminary analysis; 10 women, (14.7%) made a decision about having prophylactic oophorectomy while 53 women (77.9%) have not made a decision, and 5 women (7.4%) did not answer the questionnaire. Five of the 10 women who made a decision have gone on to have prophylactic oophorectomy. Project III, Phase II Chemoprevention Study of Ovarian Cancer: this placebo-controlled randomized protocol using 4HPR has been written, approved by the Dept. of Defense, the National Cancer Institute Chemoprevention Branch, and the FDA. It has been offered to the Gynecologic Oncology Group for implementation throughout the country by interested gynecologists. Data entry and quality control systems have been established and 14 different case report forms are finalized. To data, four women have signed consent forms, three were enrolled in the Ovarian Tissue Donation Portion of the study, and one has randomized to treatment and completed her prophylactic oophorectomy in March 2000.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2000
- Accession Number
- ADA391288
Entities
People
- Paul F. Engstrom
Organizations
- Fox Chase Cancer Center