A Computational Approach Toward Identification of Malignant Lesions of the Human Breast: The Dynamics of Magnetic Resonance Imaging Contrast Agent Uptake

Abstract

Breast tumors have a higher sodium content than normal tissue. Thus, sodium magnetic resonance imaging (MRI) could prove to be a valuable non-invasive diagnostic for Breast Cancer. MRI is commonly used in clinical settings to image the interior of the human body. Currently, all clinical MRI protocols are sensitive to water or fat. Adjustments to MRI equipment can enable the technology to be sensitive to sodium. This research presents the results of technical developments within MRI to non-invasively image sodium content in a human breast. This imaging technology, in combination with existing MRI techniques, could lead to a new method for screening and staging the progression of breast cancer.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2000
Accession Number
ADA391318

Entities

People

  • John S. Leigh
  • Jonathan H. Kaufman

Organizations

  • University of Pennsylvania

Tags

Communities of Interest

  • Advanced Electronics
  • Biomedical

DTIC Thesaurus Topics

  • Arthritis
  • Biomechanical Engineering
  • Breast Cancer
  • Cartilage
  • Chemistry
  • Connective Tissue
  • Diseases And Disorders
  • Joints (Anatomy)
  • Magnetic Resonance
  • Magnetic Resonance Imaging
  • Materials
  • Mechanical Properties
  • Mechanics
  • Modulus Of Elasticity
  • Neoplasms
  • Resonance
  • Two Dimensional

Fields of Study

  • Medicine
  • Physics

Readers

  • Computer Vision.
  • Molecular Biology and Genetics
  • Neuroscience