Durability of Skin Exposure Reduction Paste Against Chemical Warfare Agents (SERPACWA) When Worn Under Protective Clothing
Abstract
Skin Exposure Reduction Paste Against Chemical Warfare Agents (SERPACWA), previously known as Topical Skin Protectant (TSP), was developed to augment the protection afforded by chemical protective clothing. Although the Food and Drug Administration (FDA) approved the New Drug Application (NDA #21-084) as a safe and effective topical drug for its intended use, the FDA and the U.S. Army Combat Developers requested additional studies to determine the specific guidance required to optimize the field use of SERPACWA. The purpose of the current experiments was twofold: 1) to determine the degree of protection that SERPACWA provided against a vasodilatory challenge at 8, 16, 12 and 24 hours of wear; and 2) to determine when SERPACWA should be re-applied to the skin to provide optimal protection.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 01, 2001
- Accession Number
- ADA396324
Entities
People
- L. A. Stephenson
- L. Levine
- M. J. Mccreery
- S. B. Robinson
- W. A. Latzka
Organizations
- United States Army Research Institute of Environmental Medicine