Determinants of Stress Fracture and Bone Mass in Elite Military Cadets
Abstract
Longitudinal measurements of BMD indicate that some, but not all, cadets are still gaining bone mass. Gain of hip and spine bone mass in women who had regular menstrual cycles was significantly greater than then in women who had 6 or fewer cycles (p < 0.05). Calcium intake by female cadets was adequate (X-bar=l200 mg/day) but calcium was not significantly related to bone loss or gain in females. In male cadets, history of high exercise and calcium intake was related to baseline bone mass and predictors of longitudinal changes are currently being evaluated. In this cohort of cadets there were 119 confirmed fractures in 79 (male =50 and female =29) cadets during the first 3 years. In a nested matched case control study (n=128) cadet blood samples were analyzed for indices of bone turnover and calcium homeostasis. There were no stress fracture related differences in these variables. Collagen I (COLI) Al genotype was analyzed on Caucasian cadets. Neither stress fracture nor bone density was related to COLIAl genotype. Whether this gene relates to the acquisition of peak bone mass is the subject of ongoing investigation.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 2001
- Accession Number
- ADA397626
Entities
People
- Felicia Cosman