Prostate Cancer in Nigerians, Jamaicans and U.S. Blacks
Abstract
This research attempts to develop the infrastructure for comparative studies of prostate cancer involving West Africa, the Caribbean and the United States (Ibadan, Nigeria, Kingston, Jamaica and Chicago, Illinois). Six essential areas are addressed: case recruitment, case characterization, tissue collection and storage, integrated database development, targeted laboratory expertise and pilot research. Key Research Accomplishments During Year 1: 1) established reliable recruitment and data collection strategies in Chicago and Kingston; 2) established a centralized data repository in Chicago consisting of demographic and clinico-pathologic histories and tissue (serum/plamsa, leukocytes, erythrocytes and prostate tissue) for biochemical and molecular studies; 3) met solicitation and recruitment target in Chicago and Kingston; 4) successfully applied secure web-based technology to solve the problem of pathologists determining histologic grade of cases enrolled by consensus; 5) positioned to conduct preliminary biologic and molecular comparison of cases in from Chicago and Kingston, pending approval of the latter's assurances with OHRP; and 6) 2 manuscripts have been submitted, and 1 is in preparation from our pathology working group. Problems & Remedies: Results in Ibadan were disappointing. We plan to transfer the West African limb of the study to another site by February, 2002. Ghana (Accra) is the most promising.
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 01, 2001
- Accession Number
- ADA398067
Entities
People
- Vincent L. Freeman
Organizations
- Loyola University New Orleans