Cellular Mechanisms Regulating uPA in Hormone Refractory Prostate Cancer: A Novel Therapeutic Target

Abstract

DOD grant DAMDl7-00-1-0524 has the purpose of inhibiting the expression of two pathways critical to prostate cancer progression, one mediated by the tyrosine kinase receptor c- Met, and the second mediated by urokinase plasminogen activator (uPA) . Dr. Gary E. Gallick, Ph.D. became PI of the project upon after the departure from M.D. Anderson of Dr. Robert Radinsky. Because of the requirement for approval of change of PI and use of animals, work on this proposal commenced after January 1, 2001.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2001
Accession Number
ADA398158

Entities

People

  • Gary E. Gallick

Organizations

  • The University of Texas MD Anderson Cancer Center

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Cancer
  • Cell Line
  • Cells
  • Inhibition
  • Inhibitors
  • Metastasis
  • Neoplasms
  • Plasminogen
  • Prostate
  • Prostate Cancer
  • Tumor Cell Line

Fields of Study

  • Physics

Readers

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  • Research Science/Academic Research