Phage Display Breast Carcinoma cDNA Libraries: Isolation of Clones Which Specifically Bind to Membrane Glycoproteins, Mucins, and Endothelial Cell Surface

Abstract

We attempted to identify phage display cDNA clones that exhibited proteins with carbohydrate affinity, using libraries constructed in mid copy display T7Select 10-3 vector. Although we hoped that higher affinity with multiple number of capsid fusions would facilitate the screening of those clones, the attempts have been unsuccessful.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 2001
Accession Number
ADA398247

Entities

People

  • Fumichiro Yamamoto

Organizations

  • Sanford Burnham Prebys Medical Discovery Institute

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Biomolecules
  • Breast Cancer
  • Carbohydrates
  • Carrier Proteins
  • Cells
  • Chemical Compounds
  • Electronic Mail
  • Endothelial Cells
  • Genetic Structures
  • Glycoproteins
  • Information Operations
  • Membranes
  • Neoplasms
  • Proteins

Fields of Study

  • Biology

Readers

  • Immunology
  • Molecular Genetics