Do the Effects of Exercise on Breast Cancer Vary With Environments

Abstract

We propose to study 10 healthy postmenopausal women who normally exercise. We will ask these women to have their blood-drawn before and after an hour of exercise outdoors on a sunny day and then a week later indoors on a treadmill in a room with only indoor lighting. We propose that exercise done outdoors will have a different effect on vascular endothelial growth factor (VEGF), hypoxia inducible factors 1 a and beta, vitamin D activity, and estrogen metabolism as measured by the ratio of 2 hydroxyestrone and 16 alpha- hydroxyestrone. Elucidation of indoor versus outdoor influences on exercise induced metabolism may be important in understanding variations in reports of the protective nature of exercise on breast cancer prevention.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2001
Accession Number
ADA398945

Entities

People

  • Jane Teas

Organizations

  • University of South Carolina

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Blood Flow
  • Breast Cancer
  • Data Analysis
  • Electronic Mail
  • Environment
  • Estrogens
  • Growth Factors
  • Information Operations
  • Neoplasms
  • Security
  • Skeletal Muscle
  • South Carolina
  • Sunlight
  • Universities
  • Volunteers

Readers

  • Exercise and Sports Science.
  • Oncology (Cancer Research).