Discovery of a Novel Mammary Developmental and Cancer Genes Using Recessive ENU Mutagenesis

Abstract

A screen of the first round of large scale mutagenesis has been completed. Six pedigrees with members harboring mammary tumors were identified. These pedigrees were recreated from genetic backups and are now being screened using mammary biopsy. Affected females will be used to establish stable breeding lines.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2001
Accession Number
ADA399057

Entities

People

  • Christopher J. Ormandy

Organizations

  • Garvan Institute of Medical Research

Tags

DTIC Thesaurus Topics

  • Abnormalities
  • Biomedical Research
  • Breast Cancer
  • Breeding
  • Cancer
  • Carcinoma
  • Diseases And Disorders
  • Electronic Mail
  • Genes
  • Genetics
  • Genome
  • Glands
  • Mammary Glands
  • Mutations
  • Neoplasms
  • Phenotypes
  • Resonant Frequency

Fields of Study

  • Biology
  • Medicine

Readers

  • Molecular and genetic basis of cancer.

Technology Areas

  • Biotechnology