Screening for Breast Cancer Using Near Field Infrared Spectroscopy of a Single Strand of Hair

Abstract

A recent Australian study has used synchrotron x-ray diffraction to identify changes in the structure of hair that may be linked to either the occurrence of breast cancer, or the increased predisposition to breast cancer because of the breast of a mutation of the BRCA1 gene. We would like to develop a new method for the screening of breast cancer based on infrared spectroscopy of a single strand of human hair. Our study will provide an independent test of the proposed link between hair structure and breast cancer. In addition it may also provide a detailed understanding of how deposits in hair are linked to the formation of breast cancer, at a molecular level. Synchrotron x-ray studies require the use of large accelerators. Our proposed instrument is a table-top device with the possible potential for rapid, non-invasive, safe and inexpensive screening. This work involves an interdisciplinary collaboration between physicists, epidemiologists, and oncologists at Boston University Center for Photonics, Dartmouth College, and Dartmouth Hitchcock Medical Center.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2001
Accession Number
ADA399313

Entities

People

  • M. K. Hong
  • Shyamsunder Erramilli

Organizations

  • Boston University

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Biomedical Research
  • Breast Cancer
  • Classification
  • Electronic Mail
  • Information Operations
  • Infrared Spectroscopy
  • Maryland
  • Massachusetts
  • Monitoring
  • Near Field
  • Neoplasms
  • Security
  • Spectroscopy
  • Universities

Fields of Study

  • Physics

Readers

  • Molecular and genetic basis of cancer.
  • Trauma Surgery or Emergency Medicine.
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.