Stage I Breast Cancer and Bone Mass in Older Women
Abstract
The specific aims of the study are I) to assess the bone mineral density of women 65 years of age and older with breast cancer in comparison with the bone mineral density of same aged women with normal mammograms; 2) to examine the risk factors associated with breast cancer and low bone mass in these two groups of women; 3) to develop a model based on the study population to determine the predictive value of low bone mass for risk of breast cancer. During the three years of this study, a total of 300 women (150 with breast cancer and 150 with a normal mammogram) aged 65 and older will be recruited from oncology and radiology offices to participate in a study consisting of one clinic visit. At the clinic visit, each subject will complete questionnaires detailing medical history, health habits, reproductive history, and medications. Height and weight will be measured. A blood sample will be drawn for storage. Bone mineral density will be measured at the forearm, hip, lumbar spine (Ll-L4), and whole body using dual energy x-ray absorptiometry (DXA). The results of this study can be used I) to identify the likelihood of low bone mass in older women with breast cancer; 2) to identify the risk factors that are common to both low BMD and breast cancer; and 3) to determine the feasibility of discontinuing mammography after 65 in women with low bone mass.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2001
- Accession Number
- ADA399382
Entities
People
- Diane L. Schneider
- Donna Kritz-silverstein
Organizations
- University of California, San Diego