Impact of Breast Cancer Treatments on Gonadal Function and Reproductive Health
Abstract
In this third year of funding, we completed recruitment for phases one and two of the study. We now have questionnaire data on 577 breast cancer survivors between 2-10 years post-diagnosis. These data include information on demographics, menstrual and reproductive history, medication history, pregnancy/fertility history, past and current symptoms that may be menopause related, use of alternative therapies, diet and physical activity levels, as well as standardized measures of health-related quality of life. We also have bone density measurements and biologic data on a subset of 346 of these women. We plan to begin analyzing these data extensively, comparing women in four treatment categories: no adjuvant therapy; chemotherapy alone; tamoxifen alone; and chemotherapy plus tamoxifen. Phases three and four of the study are ongoing. For phase three, we have already collected neurocognitive functioning data on 54 women, and are continuing to collect data on women with no history of breast cancer, to be used as controls. For phase four, we have already completed 18-month follow-up bone mineral density tests on 38 women, and will continue to recruit women for this phase of the study as their 18-month phase two anniversaries come up.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2001
- Accession Number
- ADA400013
Entities
People
- Patricia A. Ganz
Organizations
- University of California, Los Angeles