Dynamic Functional Mammoscopy: A Non-Ionizing Imaging Technique Enhancing Early Detection of Breast Cancer

Abstract

The imaging technology of Dynamic Functional Optical Mammoscopy (DFOM) has been used to scan patients scheduled for biopsy of breast lesions. These patients were scheduled for core or excisional breast biopsy on the basis of equivocal mammographic and ancillary clinical findings within ACR BI-RADS(TM) categories 3 or 4. Analysis of test results of 47 patients shows that the DFOM detected cancer in nine of the 11 patients in whom biopsies confirmed malignant lesions giving a sensitivity of 82%. DFOM also correctly identified 24 of 36 benign lesions giving a specificity of 67%. In clinical practice. the adjunctive use of DFOM would have decreased the percentage of biopsies that turn out to be benign from 36/47 (77%) to 12/47 (26%). The negative predictive value, the chance that a negative DFOM result truly indicates a benign lesion, was 24/26 (92%).

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2000
Accession Number
ADA400070

Entities

People

  • Suzanne Smith

Organizations

  • Columbia University

Tags

DTIC Thesaurus Topics

  • African Americans
  • Biomedical Research
  • Breast Cancer
  • Detection
  • Electronic Mail
  • Illumination
  • Imaging Techniques
  • Information Operations
  • Institutional Review Board
  • Light Emitting Diodes
  • Neoplasms
  • New York
  • Pathology
  • Pilot Studies
  • Sensitivity
  • Tissues

Fields of Study

  • Medicine

Readers

  • Oncology and Biomarker-Based Cancer Detection.