4,4' Methylenedianiline (MDA) in the Construction Industry

Abstract

On August 10, 1992, the Occupational Safety and Health Administration (OSHA) issued a final standard regulating occupational exposure to 4,4' Methylenedianiline (MDA), the result of the agency's first negotiated rulemaking effort. MDA is a light-brown crystalline solid with a faint amino-like odor. It is slightly soluble in water and very soluble in alcohol and benzene. MDA is produced commercially by the condensation of aniline and formaldehyde. Crude MDA (40 to 60 percent) is either a liquid or a hard wax-like substance. Purified MDA (99 percent) is either light yellow crystalline flakes or white granules. Routes of exposure to MDA include skin absorption, inhalation, and ingestion. Short-term (acute) overexposure to MDA produces fever, chills, loss of appetite, vomiting, and/or jaundice. Short-term contact with MDA may irritate the skin, eyes, and mucous membranes and sensitization to MDA also may occur. Long-term (chronic) overexposure may cause cancer as well as damage to the liver, kidneys, blood, and spleen.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1993
Accession Number
ADA400440

Entities

Organizations

  • United States Department of Labor

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Clothing
  • Construction
  • Digestive System Processes
  • Education
  • Emergencies
  • Employment
  • Engineering
  • Governments
  • Industrial Relations
  • Management Personnel
  • Materials
  • Measurement
  • New York
  • Occupational Safety And Health
  • Personal Protective Equipment
  • Protective Clothing
  • Protective Equipment

Readers

  • Aviation Safety Risk Assessment.
  • Missile Defense Systems.
  • Toxicology/Environmental Toxicology