Fiber Optic Metal Ion Biosensor

Abstract

The central objective of this project was to see if a fluorescence-based sensor employing a biological or biomimetic molecule as a transducer could demonstrate high sensitivity, selectivity as well as rapid and reversible response to an analyte such as Cu(II) or Zn(II). A key goal was to see if the sensor figures of merit could be optimized by modification (mutagenesis)of the transducer molecule; among the figures of merit were the affinity, selectivity, stability, and response speed of the sensor. Results of that work are described in the ONR grant Final Reports of Drs. Carol Fierke and David Christianson.

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Document Details

Document Type
Technical Report
Publication Date
May 24, 2002
Accession Number
ADA402530

Entities

People

  • Richard B. Thompson

Organizations

  • University of Maryland School of Medicine

Tags

Communities of Interest

  • Advanced Electronics
  • Biomedical
  • Sensors

DTIC Thesaurus Topics

  • Analytical Chemistry
  • Anisotropy
  • Biological Detection
  • Biosensors
  • Chemical Analysis
  • Chemistry
  • Detection
  • Detectors
  • Dynamic Range
  • Electro-Optics
  • Energy Transfer
  • Fluorescence
  • Laser Spectroscopy
  • Molecules
  • Optical Fibers
  • Spectroscopy
  • Transducers

Fields of Study

  • Chemistry

Readers

  • Military History
  • Molecular and Cellular Biochemistry
  • Nanoscale Plasmonic Nanotechnology

Technology Areas

  • Biotechnology