The Staphylococcal Enterotoxins

Abstract

Staphylococcal enterotoxins (SEs) constitute a family of related proteins whose biological toxicities include staphylococcal food poisoning (SFP), various skin disorders toxic shock syndrome (TSS), and possible involvement in autoimmune disorders. The SEs (named sequentially by letter) include SEA, B, C1, C2, C3, D, E, G, H, I, J and toxic shock syndrome toxin (TSST-1); their properties will be compared in throughout this discussion . They have been thoroughly characterized as super antigens, due to their massive impact on the immune system of the host, and their interaction with lymphoid cells has been widely studied. SE also have been shown to exert effects on endothelial cells, kidney proximal tubule cells, synovial cells, and human platelets.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 2001
Accession Number
ADA402636

Entities

People

  • Boris Iomin
  • Marti Jett
  • Rina Das
  • Roger Neill

Organizations

  • Walter Reed Army Institute of Research

Tags

DTIC Thesaurus Topics

  • Cell Physiological Processes
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Health Services
  • Lung Diseases
  • Lymphocytes
  • Medical Personnel

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology and Pathology
  • Microbial Pathology
  • Toxicology/Environmental Toxicology

Technology Areas

  • Fully Networked C3
  • Fully Networked C3 - Command and Control