Soy, Probiotics, and Breast Cancer Prevention
Abstract
The purpose of this study is to investigate the effects of soy and probiotic consumption on estrogen and phytoestrogen metabolism. The methods include in vitro studies to determine the intestinal microflora responsible for phytoestrogen metabolism, and a human feeding study in which 20 postmenopausal breast cancer survivors and 20 controls consume four different dietary supplements for six weeks each. The supplements were: 1) soy powder; 2) soy powder + probiotic; 3) milk power; 4) milk powder plus probiotic. Urine was collected for three days before the study began and for three days at the end of each diet period, for evaluation of urinary estrogen and phytoestrogen metabolites. Food records were collected on the same days as the urines. Feces were collected before the study began and at the end of each diet period, for evaluation of intestinal microflora profiles. At this point, both in vitro and human studies have been completed. All subjects have completed the human feeding study, urines have been collected and processed and fecal samples have been analyzed. During the final year, the urine samples will be analyzed, data analyses will be performed, and manuscripts will be prepared for publication.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2001
- Accession Number
- ADA403323
Entities
People
- Mindy S. Kurzer
Organizations
- University of Minnesota