Body Fat Phenotypes, Sex Hormones and Breast Cancer Risk in Post Manopausal African-American Women

Abstract

African-American (AA) women have the highest breast cancer mortality rate in the U.S. Despite reports suggesting that breast cancer in AA women might be a biologically more aggressive disease, AA women, especially postmenopausal AA women, remain one of the least studied populations in this country, with very little known about their sex hormone profile. Recent findings have suggested that body fat distribution may be a better marker for breast cancer risk than degree of obesity. This is a 5 years cross-sectional study to determine the association between body fat phenotypes and sex hormone profile in postmenopausal AA women. For year two, we were able to continue aggressive recruitment strategies to increase the total number of women interested in participating in the study from 162 for year one to almost triple at 459. This continues to be a very challenging study to undertake, but our study team is undeterred. To date 23 of 43 eligible women have gone through the study protocol. Hormone values for 20 of these women have already been determined. Results from preliminary analyses of hormone and other data on women who have completed the study protocol are presented in this report.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2001
Accession Number
ADA403374

Entities

People

  • Junaidah B. Barnett

Organizations

  • Tufts University

Tags

DTIC Thesaurus Topics

  • African Americans
  • Body Composition
  • Breast Cancer
  • Data Analysis
  • Diseases And Disorders
  • Families (Human)
  • Health
  • Hormones
  • Information Science
  • Materials
  • Neoplasms
  • New England
  • Phenotypes
  • Physical Activity
  • Public Health
  • Risk Factors
  • Sex Hormones

Readers

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