Improved MR Images of Breast Lesions with Fast Spectroscopic Imaging
Abstract
Work during the first year of funding resulted in development of a high resolution echo planar imaging sequence for our whole-body GE SIGNA scanners. This sequence was tested in phantoms and volunteers. During the second year of funding, we increased the number of normal volunteers scanned (n=15) and scanned women with biopsy-confirmed breast cancer (n=7) and women with suspicious lesions on mammography (n=5). We developed and implemented improved methods of data analysis and performed quantitative comparisons of high spectral and spatial resolution (HiSS) images with conventional images. These comparisons demonstrate that under our experimental conditions HiSS provides improved fat-suppression, improved contrast, texture, edge delineation, and increased sensitivity to contrast media, relative to conventional MRT. These results are described papers in press in Radiology and Academic Radiology as well as another manuscript in progress. At the same time, we have continued to develop software for our GE scanners and now have a version of high resolution EPSI that runs on our recently upgraded SIGNA scanners. This version of the pulse sequence is incorporated into the standard clinical breast imaging protocol this will allow us to increase the number of patients who are scanned after informed consent is obtained.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2001
- Accession Number
- ADA403614
Entities
People
- Gregory S. Karczmar
Organizations
- University of Chicago