Accelerated Tumor Cell Death by Angiogenic Modifiers

Abstract

Because of the inherent stability of endothelial cells and the importance of this cell type for the proliferation of both localized and disseminated cancers, anti- angiogenic therapy is an attractive target for the investigation and further development of novel therapeutic approaches to cancer metastasis. The purpose of this proposal is to assess molecular mechanism 5 underlying synergy between squalamine and vascular endothelial growth factor 5 (VEGF)

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2001
Accession Number
ADA403672

Entities

People

  • Chia-ling Hsieh
  • Leland W. Chung
  • Michael Bradley
  • Mitchell H. Sokoloff

Organizations

  • University of Virginia

Tags

DTIC Thesaurus Topics

  • Biological Factors
  • Cell Physiological Processes
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Gene Therapy
  • Genetics
  • Health Services
  • Oncology
  • Peptide Growth Factors
  • Peptides
  • Prostate Cancer
  • Proteins

Fields of Study

  • Chemistry

Readers

  • Oncology (Cancer Research).