Prostate Cancer in Nigerians, Jamaicans and U.S. Blacks

Abstract

This research attempts to develop the infrastructure for comparative studies of prostate cancer involving West Africa, the Caribbean and the United States. Six essential areas are addressed: case recruitment, case characterization, tissue collection and storage, integrated database development, targeted laboratory expertise and pilot research. Key Research Accomplishment During Year 1: (1) changed title of project to "Prostate Cancer in Nigerians, Jamaicans and U.S. Blacks"; (2) maintained the centralized data repository in Chicago consisting of demographic and clinico-pathologic history and tissue (serum/plasma, leukocytes, erythrocytes and prostate tissue) for biochemical and molecular studies; (3) sustained case enrollment and data collection in Chicago; (4) extension of Chicago-area recruitment to a busy private practice; (5) obtained administrative and ethics approval of study site in Jamaica, with re-activation of protocol there; (6) met solicitation and recruitment target in Chicago (Year 1 & 2) and Kingston (Year 1 only); (7) a recruitment site in Accra, Ghana is being established; (8) preliminary biologic and molecular comparison of cases from Chicago and Kingston, planned for this Spring, 2002; (9) 3 manuscripts from our pathology working group under review. There are no other reportable outcomes for Year 2. In conclusion, steady progress is being made. Results of the biochemical and molecular studies and clinical comparison should lay the foundation for future grants. We anticipate requesting a no-cost extension to complete 12 months of data collection once the study is approved there.

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Document Details

Document Type
Technical Report
Publication Date
Mar 01, 2002
Accession Number
ADA403861

Entities

People

  • Vincent L. Freeman

Organizations

  • Loyola University New Orleans

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • African Americans
  • Blood
  • Databases
  • Electronic Mail
  • Health Services
  • Leukocytes
  • Medical Personnel
  • Neoplasms
  • Organizational Structure
  • Pathology
  • Prostate
  • Prostate Cancer
  • Storage
  • Tissues
  • United States

Readers

  • International Relations, focusing on Korea-Africa and North Korea-South Korea relations, and Nigeria-Latin American Relations.
  • Oncology and Biomarker-Based Cancer Detection.
  • Technical Research and Report Writing.