Magnetic Resonance Studies of Photosensitizers and Their Effect in Tumors
Abstract
A significant part of the project is the tumor imaging, spectroscopic investigations, and detailed statistical analysis following the administration of photo sensitizers and irradiation with the laser light at the appropriate wavelength. The presence of the photosensitizer in the tumor will be detected in the in vivo tumor model in mice. The growth and maintenance of cells, inoculating the cells and observe the growth pattern, and selecting the tumors of appropriate size for MR studies constitutes a small but essential step towards this goal. Following the grant transfer I have added a new part- time research assistant(technician) to perform some of the studies and help the P.1 and the team with data collection, maintaining the records, and to ultimately develop into a flill team member. The basic operation of our instrument, preliminary optimization of the MR imager to record spectral data in the in vivo and in vitro state has also been pursued by the student under the supervision and guidance of the P.1. The student has learnt many skills and knowledge in a short time. In particular, the technician has received training in animal handling, blood drawing under anesthesia, anesthetization of rodents using isofiurane and N2O gas, or injectables such as ketamine and xylazine.
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 2001
- Accession Number
- ADA404594
Entities
People
- Subbaraya Ramaprasad
Organizations
- University of Nebraska Medical Center