A Method for Simulating Mammograms

Abstract

This project is to facilitate research in digital mammography and related technologies, in particular computer aided diagnosis and image processing. A major limitation to the rapid development and subsequent clinical implementation of these technologies is the lack of a standardized set of mammograms to be used in development and evaluation. We are developing a method to produce simulated mammograms. The method relies on a model of image formation that takes into account the absorption of x-rays in the phosphor, subsequent conversion to light and the scattering of the light before escaping the phosphor. The model also takes into account the finite thickness of the phosphor, the divergence of the x-ray beam, scattered radiation, and noise due to film granularity and from the film digitizer. Almost all the components of the model are completed and computer code is being written. The model requires as input high fidelity images of breast tissue and of breast lesions. We are now testing the model using x-ray phantoms. We are comparing simulated images created based on a high quality film radiograph to an image acquired using a mammographic screen-film system.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2001
Accession Number
ADA404610

Entities

People

  • Robert Nishikawa

Organizations

  • University of Chicago

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Availability
  • Biomedical Research
  • Breast Cancer
  • Classification
  • Electronic Mail
  • Illinois
  • Information Operations
  • Instructions
  • Maryland
  • Monitoring
  • Neoplasms
  • Security
  • Standards
  • Universities

Fields of Study

  • Medicine
  • Physics

Readers

  • Computational Modeling and Simulation
  • Nuclear and Radiation Engineering.
  • Oncology and Biomarker-Based Cancer Detection.