Lifetime Alcohol Exposure and Breast Cancer Risk

Abstract

This case-control study was an examination of breast cancer risk in relation to lifetime alcohol consumption. We interviewed 1,181 women with breast cancer (295 pre- and 886 post-menopausal women), age 35-79, from Erie and Niagara counties in New York State, all with incident, pathologically confirmed breast cancer. A total of 2,181 controls were interviewed; controls were randomly selected and frequency matched to cases on age, race and county of residence. Participants complete a computerized interview, which focused on in-depth lifetime alcohol consumption history. Potential confounding factors were also assessed. A specimen bank is being used to store biological samples for future research of serum and urinary markers of hormones, hormone metabolites, vitamins, genetic polymorphisms and blood levels of antioxidants and oxidative stress. At the completion of the study, 969 blood samples were stored for cases and 2,016 for controls. Data collection has been completed. Some data analysis has been completed as well and preliminary findings are included. Data analysis will continue to utilize this excellent resource.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 2001
Accession Number
ADA404717

Entities

People

  • Jo L Freudenheim

Organizations

  • University at Buffalo

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Alcohol Consumption
  • Breast Cancer
  • Data Analysis
  • Diseases And Disorders
  • Environmental Exposure
  • Genetic Variation
  • Genetics
  • Geographic Information Systems
  • Health Services
  • Institutional Review Board
  • Medical Personnel
  • Metabolism
  • Neoplasms
  • New York
  • Oxidative Stress
  • Physicians
  • Public Health

Fields of Study

  • Medicine

Readers

  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.

Technology Areas

  • Biotechnology