Tagging of Breast Tumors for Excision and Specimen Radiography and of Sentinel Nodes for Ultrasound-Guided Localization Using Novel Particulate Agents

Abstract

During the first year, we identified a radiopaque tumor-marking agent and optimized the dose. During the second year we worked on coloring the agent and worked on the second agent for sentinel node detection to improve upon the water-soluble dye. Scope: We could not color the radiopaque perfluorocarbon (PFC) emulsion but successfully suspended India Ink within it. The optimum dose of the mixture was injected in tumors. We followed the black tract to locate and remove the tumor at 72 hours. The resected specimen was then radiographed. We began the work to accomplish the 3rd goal, the identification of the sentinel node.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 2001
Accession Number
ADA404734

Entities

People

  • Robert F. Mattrey

Organizations

  • University of California, San Diego

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Breast Cancer
  • California
  • Contrast
  • Detection
  • Emulsions
  • Excision
  • Guidance
  • Imaging Techniques
  • Lymph Nodes
  • Lymphatic System
  • Materials
  • Neoplasms
  • Particles
  • Particulates
  • Radiography
  • Ultrasounds

Fields of Study

  • Medicine

Readers

  • Chemistry (specifically Chemical Fluorescence)
  • Oncology and Biomarker-Based Cancer Detection.
  • Trauma Surgery or Emergency Medicine.