Ovarian Cancer Prevention Program
Abstract
The goals of this research are to develop interdisciplinary studies of the etiology, biology and prevention of ovarian cancer. Project I, Ovarian Cancer Consortium has registered 687 participants including 234 patients representing 320 families. The Core Laboratory has collected, processed and banked biospecimens from 496 subjects. Project II, Facilitating Decision Marking About Prophylactic Oophorectomy: baseline data on 80 women are available for preliminary analysis; 15 women, (19%) made a decision about having prophylactic oophorectomy while 66 women (76%) have not made a decision, and 4 women (5%) did not answer the questionnaire. Fifteen women said they would likely have a prophylactic oophorectomy in the near future. Project II!, Phase II Chemoprevention Study of Ovarian Cancer: this placebo-controlled randomized protocol using 4HPR has been written, approved by the Dept. of Defense, the National Cancer Institute Chemoprevention Branch, and the FDA. The Gynecologic Oncology Group has implemented the study throughout the country for interested gynecologic oncologists. Data entry and quality control systems have been established and 14 different case report forms are finalized. Seven women have signed consent forms, 6 were enrolled in the Ovarian Tissue Donation Portion of the study, and one has randomized to treatment and completed her prophylactic oophorectomy in March 2000.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 2001
- Accession Number
- ADA406118
Entities
People
- Paul F. Engstrom
Organizations
- Fox Chase Cancer Center