The Anthrax Vaccine Debate: A Medical Review for Commanders
Abstract
There are two distinct yet related aspects to the debate over the safety and efficacy of the anthrax vaccine. An assessment of the clinical safety and efficacy of the anthrax vaccine. The policy level decision to vaccinate military personnel based on intelligence reports and assessments. The policy decision to vaccinate is based on an assessment of relative risk. The risk to an individual of developing side effects and complications after vaccination versus, the risk that Defense Department (DoD) personnel may be exposed to anthrax during an attack. Anthrax causes disease in humans through three mechanisms: cutaneous, gastrointestinal, inhalation. Cutaneous anthrax occurs primarily in unvaccinated workers in goat hair and wool factories. Veterinary practices and vaccination have eliminated anthrax infection as an occupational risk. Inhalation anthrax is the most lethal. Death occurs in nearly 100 percent of victims with symptoms. Inhalation anthrax is the 100% most likely to be used in biological weapons. Requires aerosolization of anthrax spores down to the proper particulate size for inhalation. Aerosolization of anthrax spores is technically difficult to achieve.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 2001
- Accession Number
- ADA407578
Entities
People
- Richard A. Hersack
Organizations
- Air University